This product is inhaled into the lungs using the Breezhaler®.
Why is it prescribed?
Indacaterol maleate is used for the treatment of airflow obstruction in patients with COPD, including chronic bronchitis and emphysema. Indacaterol is used only in patients who are 18 years of age or older.
- Inhale the contents of one capsule through the mouth each day, everyday at the same time, using the Onbrez® Breezhaler® inhalation device even when you have no breathing problems or other symptoms of COPD.
- You may inhale this medication on an empty stomach or after food or drink.
- Speak with your pharmacist or healthcare professional about proper use of the Breezhaler® device. The device should make a whirring sound during inhalation when used correctly. As well, you will notice a sweet taste as you inhale the medication
- Capsules must always be stored in the blister, and only removed immediately beforeuse
- Never place a capsule directly into the mouthpiece of the inhalation device
- Do not press the piercing buttons more than once Never blow into the mouthpiece of the inhalation device
- Always release the push buttons before inhalation
- Never wash the inhalation device with water. Keep it dry.
- Never take the inhalation device apart
- Do not store the capsules in the Breezhaler® inhalation device
- Always keep the Breezhaler® and capsules in a dry place
- If you forget a dose, inhale the next dose on the usual time the next day. Do not take a double dose to make up for a forgotten dose.
See other products used in the treatment of •COPD •
Adults 18 years of age and older: The recommended dosage of Onbrez® is one 75mcg capsule used with the Breezhaler® device once daily at the same time each day.
Onbrez® capsules should be stored in the blister pack and only removed immediately before use.
Indacaterol maleate is a long-acting beta2-agonist for use as a long-term, once-daily maintenance bronchodilator. It relaxes the muscles in the walls of the small air passages in the lungs. This helps open up the airways
￼for 24 hours, making it easier for air to get in and out and prevent symptoms, such as wheezing and shortness of breath.
Indacaterol has a rapid onset of action and a long duration of action.
The most commonly reported adverse reactions are:
- irritation of the mouth or throat
- muscle cramps
- Indacaterol maleate contains the same black box warning as other long-acting beta2-agonists. Long-acting beta2-adrenergic agonists increase the risk of asthma-related death. This warning is based on a large U.S. study of salmeterol and is considered a class effect.
- Indacaterol is not indicated for use in asthma.
- This medication is not for treatment of sudden, severe symptoms of COPD. A rescue inhaler should be used in these cases.
Do not use if you have an allergy to indacaterol.
Use indacaterol with caution if you have:
- heart problems, such as rapid or irregular heart beat or abnormal electrical signal called “prolongation of the QT interval”
- high blood pressure
- thyroid problems
- other medications similar to indacaterol
- medicines that decrease the level of potassium in your blood
- beta-blockers used in the treatment of hypertension or other cardiac problems (e.g. propranolol) or in the treatment of glaucoma (e.g. timolol)
Pregnancy and breastfeeding - Human data is limited. Contact your doctor or pharmacist before using.