Aclidinium Bromide

Why is it prescribed?

Aclidinium bromide is an anticholinergic long-acting bronchodilator used for the maintenance treatment of bronchospasm associated with chronic obstructive pulmonary disease (COPD), including chronic bronchitis and emphysema.  To receive the most benefit from this medication, it must be used regularly. Do NOT use this medication to treat episodes of shortness of breath.

Products that have this ingredient include •Tudorza® Genuair® •Duaklir® Genuair® •

See other drugs used in the treatment of •COPD •

Along with its benefit, aclidinium bromide may cause unwanted effects. Possible side effects include:

  • headache
  • inflammation or irritation of the nose and throat
  • cough
  • diarrhea
  • sinusitis
  • vomiting
  • hoarseness
  • dizziness

Stop taking this medication and seek medical help if you experience:

  • New or worsened pressure in your eyes, eye pain or discomfort, blurred vision, seeing halos of bright colours around lights, red eyes. 
  • Tightness of the chest associated with coughing, wheezing, or breathlessness immediately after inhalation  
  • Serious allergic reactions: rash, hives, swelling of the face, mouth, lips and tongue with or without breathing problems


Aclidinium bromide is a long-acting antimuscarinic agent used by inhalation through the mouth.  It works by relaxing the muscles that surround the airways. This opens the air passages and makes breathing easier.


  • Aclidinium bromide is for maintenance therapy only and should not be used as a rescue inhaler during a sudden episode of bronchospasm.
  • Aclidinium bromide may cause paroxysmal bronchospasm in some patients. If this happens, discontinue use.
  • Aclidinium should be used cautiously in patients with narrow- angle glaucoma. If symptoms of acute narrow-angle glaucoma such as, eye pain, visual halos, or blurred vision develop, consult your physician immediately.
  • Aclidinium should be used cautiously in patients who have urinary retention. If passing urine becomes difficult, or painful, consult your physician immediately.
  • Patients with a hypersensitivity to aclidinium bromide should not use it.
  • Patients who have a hypersensitivity to atropine should use aclidinium with caution. The two are structurally similar and hypersensitivity reaction may occur.
  • Patients with a severe allergy to milk protein should not use aclidinium.

Use in pregnancy and breastfeeding: Limited human data available at this time.  Use only if benefits outweigh risks.  Consult your doctor or pharmacist before use.

Page Last Updated: 25/11/2015