Olodaterol Hydrochloride

Why is it prescribed?

Olodaterol is long-term, once-daily maintenance bronchodilator treatment of airflow obstruction in patients with chronic obstructive pulmonary disease (COPD), including chronic bronchitis and/or emphysema.

Products that have this ingredient include •Striverdi® Respimat® •Inspiolto® Respimat® •

See other drugs used in the treatment of •bronchitis •COPD •emphysema (COPD) •

The most commonly reported adverse reactions are:

  • cough
  • dizziness
  • headache
  • dry mouth
  • nausea
  • inflammation of the throat and nasal passages
  • symptoms of the common cold
  • nervousness, tremor
  • fatigue

Serious side effects that require immediate medical attention:

  • allergic reaction -  rash, hives, swelling of the face, lips, tongue or throat, difficulty swallowing or breathing
  • wheezing or coughing and difficulty breathing
  • chest pain, trouble breathing, swelling of the hands or feet, heartburn

Olodaterol is a long-acting beta2-agonist used as an inhalation for treating patients with chronic obstructive pulmonary disease (COPD). It relaxes the muscles in the breathing passages allowing for easier breathing and relief of symptoms such as shortness of breath and coughing.

  • Olodaterol is not indicated to treat acute deteriorations of COPD and is not indicated to treat asthma.
  • Long-acting beta2-adrenergic agonists (LABA), such as olodaterol, may increase the risk of asthma-related death. All LABA are contraindicated in patients with asthma without use of a long-term asthma control medication.
  • Olodaterol should not be started in patients with acutely deteriorating COPD, which may be a life threatening condition, or used as rescue therapy for acute episodes of bronchospasm. Acute symptoms should be treated with a relief (short-acting) inhaled medication.
  • Olodaterol should not be used more often than recommended, at higher doses than recommended, or in conjunction with other medications containing long-acting beta2 agonists as an overdose may result. Cli
  • Olodaterol may produce paradoxical bronchospasm that may be life threatening. Stop using immediately if this occurs.
  • Use with caution in patients with
    • seizures
    • high blood pressure
    • heart problems such as fast or irregular heart beat
    • overactive thyroid
    • diabetes
  • This medication should not be used in children. It is not known if olodaterol is safe and effective in children.
  • The following may interact with olodaterol:
    • antidepressants, in particular tricyclic antidepressants and monoamine oxidase inhibitors (MAOIs)
    • medicines that decrease the level of potassium in your blood. These include diuretics (also known as water pills and are used to treat high blood pressure e.g. hydrochlorothiazide)
    • Other bronchodilators such as methylxanthines (e.g. theophylline)
    • steroids (e.g. prednisolone)
    • beta-blockers used in the treatment of high blood pressure or other heart problems (e.g. propranolol) or in the treatment of glaucoma (e.g. timolol)

Use in pregnancy and breastfeeding: Human data is lacking at this time.  Contact your doctor or pharmacist before using.

Page Last Updated: 25/11/2015