Common side effects of Amikacin include:

• diarrhea,
• hearing loss,
• spinning sensation,
• numbness,
• skin tingling,
• muscle twitching and convulsions,
• dizziness,
• ringing or roaring in the ears,
• allergic reactions,
• Clostridioides difficile associated diarrhea (C. diff),
• skin rash,
• drug fever,
• headache,
• numbness and tingling,
• tremor,
• nausea,
• vomiting,
• increase in white blood cells,
• joint pain,
• anemia,
• low blood pressure,
• low blood magnesium.

Amikacin Injection is an aminoglycoside antibiotic. Antibiotics work by killing or slowing the growth of certain types of bacteria that cause the infection.

Do not use amikacin if:

• you are allergic to amikacin or to any ingredients in the formulation
• you are allergic to aminoglycosides

Talk to your health care provider if you:

• have kidney problems.
• have hearing or balance problems.
• have myasthenia gravis (a muscle condition) or Parkinson’s disease.
• have asthma.
• have sulfite sensitivity

The following may Interaction with amikacin:

• Other antibiotics 
• Amphotericin B
• Anti-cancer drugs, such as cisplatin.
• Potent diuretics, such as ethacrynic acid, furosemide and mannitol
• Neuromuscular blocking agents (muscle relaxants such as tubocurarine, succinylcholine and decamethonium)
• Anesthetic agents such as those used during surgery.
• Any drug that may cause kidney or hearing problems

Use in pregnancy: Although risk is thought low, amikacin does cross the placenta and negative impact to newborn's hearing have been reported

Use in breastfeeding: Amikacin is considered compatible with breastfeeding.