This product is taken orally.
Why is it prescribed?
Rifabutin is used to treat tuberculosis and Mycobacterium avium complex (MAC) disease.
- Do not stop taking Mycobutin® unless directed by your physician as this could cause the infection to return.
- Take this drug at the same time every day.
- Swallow the capsules whole with a drink of water.
- If this medication makes you feel nauseous, you can take one capsule twice a day. In this case, take with food.
- If you forget to take a dose, take it as soon as you remember, unless it is time for your next dose. Do not take a double dose to make up for a missed dose.
- Store Mycobutin® at room temperature
See other products used in the treatment of •tuberculosis •
The usual dosage is 300mg by mouth once daily or 3 times/week.
Rifabutin is an antibiotic that treats infections caused by germs (bacteria) called mycobacteria. Mycobacteria cause infections such as tuberculosis and Mycobacterium avium complex (MAC) disease.
More common side effects:
- Abdominal or stomach pain
- bad, unusual, or unpleasant (after) taste in the mouth
- bloated or full feeling
- change in taste
- discoloration of the urine
- excess air or gas in the stomach or intestines
- passing gas
- trouble sleeping
Check with your doctor immediately if any of the following side effects occur:
- Black, tarry stools
- chest pain
- itching or skin rash
- loss of appetite
- painful or difficult urination
- sore throat
- ulcers, sores, or white spots in the mouth
- unusual bleeding or bruising
- unusual tiredness or weakness
Do not use rifabutin if:
- If you are allergic (hypersensitive) to this drug.
- If you are allergic to any drug containing rifamycin.
Make sure you tell your doctor if you have any other medical problems, especially:
- Inflammation of the muscle
- Severe kidney disease
The following drugs may interact with rifabutin:
- medications to treat diabetes
- acetylsalicylic acid (ASA)
- medications to suppress the immune system like cyclosporine and tacrolimus
- quinidine or digitalis (digoxin is okay)
- phenytoin (Dilantin)
- medications to treat fungal infections like fluconazole, itraconazole, posaconazole, voriconazole, ketoconazole and miconazole
- medications to treat viral infections like indinavir, saquinavir, ritonavir or amprenavir, fosamprenavir/ritonavir, lopinavir/ritonavir and tipranavir/ritonavir
- birth control pills that have ethinyl estradiol and/or norethindrone.
Use in pregnancy: There is no human data available on safety in pregnancy. Animal studies suggest low risk.
Use in breastfeeding: There is no human data available on safety in breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.