Alpha1-antitrypsin replacement therapy is usually very well tolerated. The following side effects may occur:

• fever
• lightheadedness
• dizziness
• flu- like symptoms
• allergic-like reactions
• chills
• trouble breathing
• abnormal heartbeat
• changes in blood pressure
• chest pain

If you experience any of the above side effects, contact your health care provider.

Alpha1-antitrypsin is a naturally occurring protein in the body which protects the lungs. Alpha-1 antitrypsin deficiency (AAT deficiency) is an inherited condition that raises your risk for lung and liver disease.

Symptoms of AAT deficiency include:

• Shortness of breath and wheezing
• Repeated lung infections
• Tiredness
• Rapid heartbeat upon standing
• Vision problems
• Weight loss

Therapy with alpha1-antitrypsin restores blood levels of this protein to a desired level. 

• Alpha1-antitrypsin is made from human blood and therefore carries the risk of transmitting some viruses or illnesses.  Discuss this risk with yor physician.
• Alpha1-antitrypsin must only be given by the intravenous route.
• You should not use this medication if you are allergic to albumin or to any ingredient in the formulation or component of the container.
• You should not use this medicine if your body does not make enough immunoglobulin A (IgA), which could cause you to have an allergic reaction to blood products that contain IgA.

Use in pregnancy: It is not known whether this medication can cause fetal harm when administered to a pregnant woman or can affect reproduction capacity. It should be given to a pregnant woman only if clearly needed.

Use in breastfeeding: It is not known if this medication is passed into breast milk.  Consult doctor or pharmacist before using