Elixir de Theophylline   

This product is manufactured by Laboratoire Atlas Inc. using the ingredient theophylline.

This product is taken orally.


Why is it prescribed?

Theophylline is used to treat symptoms of conditions such as asthma, chronic bronchitis and emphysema (e.g. shortness of breath, cough, troubled breathing).

Elixir de Theophylline is meant to be taken at regular intervals around the clock,and should be taken exactly as directed by your doctor. The usual dosing regimen is every 6 to 8 hours.
Children can be very sensitive to this type of medication so it is critical that the exact dose is given each time. It is suggested that each dose be measured accurately by using the appropriate measuring spoon or syringe (ask your pharmacist if you need help selecting one).

Take before meals or with milk.
If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses. Contact your pharmacist if you are not sure what to do.
Store at room temperature (15 to 25 degrees centigrade).


Other products that have the same ingredient as Elixir de Theophylline are •AA-Theo LA tablets •Theo ER •

See other products used in the treatment of •asthma •bronchitis •bronchospasm associated with COPD •chronic bronchitis (COPD) •COPD •emphysema (COPD) •sleep apnea •

Dosing is individualized. 

Adults: Initial dose of 4 – 5 tablespoonfuls (60 – 75 mL or 320 – 400 mg theophylline). Subsequent doses should be titrated and given every 6 hours or as required based on the patient’s clinical response and or serum theophylline level which should be in the 10 – 20 mcg/mL range. Usually the dose should not exceed about 1000 mg theophylline per 24 hours.
Children Over 5 Years of Age: Initial dose of 4 – 5 mg/kg with subsequent doses being titrated and given every 6 hours or as required by the patient’s clinical response and for serum theophylline levels which should be in the 10 – 20 mcg/mL range. Generally, the total dose in 24 hours should not exceed 15 mg theophylline/kg.

Theophylline is a bronchodilator that works by relaxing smooth muscles in the bronchial tubes (air passages to the lungs) to allow air to move in and out of the lungs more easily. This permits a greater volume of air to enter the lungs and reduces the effort required to breathe.

Along with its needed effects, theophylline may cause some unwanted or undesirable effects. The frequency and severity of these effects is dependant on many factors including dose, duration of therapy and individual response. Possible unwanted effects include:

  • nausea
  • vomiting
  • diarrhea
  • nervousness
  • loss of appetite
  • headache
  • trouble in sleeping
  • irritability
  • tremor
  • abdominal discomfort


  • difficult or fast breathing
  • bloody or black tarry stools
  • seizures
  • fast or irregular heartbeat
  • blood in vomit
  • muscle twitching


  • rash
  • flushing
  • frequent urination

If you suspect that you are experiencing unwanted effects with your theophylline, check with your pharmacist.


When starting this medication, it may take a few weeks for your physician to find the dose that is right for you. The doctor may draw some blood to help him/her determine how much theophylline is in your body and then adjust your dose if there is too much or too little. The dose can vary quite significantly from person to person, even if they are the same sex, height and weight. It is very important that the correct theophylline blood level be reached as inappropriate levels may result in serious unwanted effects.
Eating or drinking large quantities of products that are high in caffeine (chocolate, tea, coffee, soft drinks) can further increase theophylline's stimulatory effects on the central nervous system (enhanced sleeplessness, agitation, uncomfortable heart beat).
Drug Interactions: Due to potentially serious interactions, it is important to inform your doctor and pharmacist of all the other medications (prescription and over-the-counter) you are taking, no matter how insignificant they may seem. Some medications can effect the amount of theophylline in the blood. The following drugs and drug classes have been known to interact with theophylline:

  • beta-blockers (e.g. propranolol)
  • cimetidine (e.g.Tagamet®)
  • ciprofloxacin (Cipro®)
  • erythromycin (e.g. Erythromid®)
  • lithium (e.g. Carbolith®)

The use of tobacco may reduce the effectiveness of theophylline.

Use is not recommended in the following situations:

  • allergy to any xanthine (e.g. aminophylline)
  • confirmed or suspected peptic ulcer disease

Caution is recommended in the following situations:

  • liver problems
  • impaired kidney function
  • people over 60 years of age
  • heart disease
  • arrhythmias (irregular heart beat)
  • coronary artery disease
  • congestive heart failure
  • newborn or premature infants
  • high blood pressure
  • pneumonia
  • fever

Use in pregnancy: Theophylline can be used in pregnancy.  Consult your doctor or pharmacist if you suspect that you may be pregnant.
Use while breastfeeding: Theophylline can be used if breastfeeding.  Consult your doctor or pharmacist before you begin breastfeeding.

Switching between brands: Products manufactured by different companies do not always deliver the same amount of theophylline, therefore the physician may have to readjust your dose after switching brands.

Page Last Updated: 05/10/2016