Most common side effects  

• injection-site reaction (pain, redness, swelling, itching, and burning sensation of the skin near where the injection was given)
• eye and eyelid inflammation, including redness, swelling, itching, and/or dryness, sometimes with blurred vision
• eye infection
• cold sores in your mouth or on your lips
• trouble sleeping
• abdominal pain/burning
• joint pain
• headache
• facial rash or redness
• parasitic infections

Dupilumab is a monoclonal antibody that blocks specific proteins called interleukin-4 and interleukin-13. By blocking the action of these interleukins, dupilumab limits the production of eosinophils from the bone marrow and lowers the number of eosinophils in the blood and lungs, which helps improve symptoms of asthma, COPD, and rhinosinusitis with nasal polyps.

• There is a chance dupilumab could cause an allergic reaction when injected. If you have had a similar reaction before, tell your doctor before you are given the injection.
• Dupilumab is not a substitute for the medicines you are already taking. It does not treat a sudden asthma or COPD attack - do not use for this reason.
• Oral or inhaled corticosteroids (e.g., prednisone, fluticasone) should not be abruptly stopped upon starting dupilumab therapy.
• Interrupting or stopping treatment with dupilumab may cause your symptoms to come back or occur more frequently. If your symptoms get worse while receiving this medication call your doctor.
• Talk to your healthcare team before receiving any vaccines.
• If you have an existing parasitic infection, live in a region where infections caused by parasites are common, or if you are travelling to such a region, talk to your doctor before using dupilumab, as it may weaken your resistance to such infections. Parasitic infections should be treated prior to starting treatment with this medication.
• Pregnancy and breastfeeding: Limited information is available. Consult your doctor or pharmacist before using.