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Apo-Clindamycin capsules

This product is manufactured by Apotex Inc. using the ingredient clindamycin.

This product is taken orally.


Why is it prescribed?

Clindamycin is used to treat infections caused by susceptible bacteria. This material will be limited to the treatment of the respiratory tract infections.

Use exactly as prescribed.  Store at room temperature.
Apo-Clindamycin can be taken with or without food. However, because it can be irritating to the throat and esophagus (food tube), it should be taken with a full glass of water to ensure the medicine is released in the stomach.
Take Apo-Clindamycin at even intervals around the clock as prescribed (e.g. every 6 hours translates to 4 times a day) until finished. Failure to take the complete course can result in incomplete elimination of the bacteria which can lead to a relapse of the infection. The prescribed course generally lasts a few days longer than symptoms of the infection (e.g. fever). Treatment usually lasts 10 days. If you miss a dose, take it as soon as possible. If it is almost time for your next dose, do not take 2 doses at once (unless you have been instructed to do so). Contact your pharmacist if you are not sure what to do.
Apo-Clindamycin® may produce an allergic reaction which can range in severity from a mild rash or itching to a life-threatening reaction. Contact your doctor or pharmacist if you experience rash, itching, fever, difficulty breathing, chest tightness or anything else that alarms you.
If diarrhea, bloody stools, stomach cramps occur during or after treatment contact your doctor or pharmacist. Do not treat the diarrhea without permission from your doctor.


Other products that have the same ingredient as Apo-Clindamycin capsules are •Auro-Clindamycin capsules •Dalacin C® capsules •Dalacin C® suspension •Jamp-Clindamycin capsules •Riva-Clindamycin capsules •Teva-Clindamycin capsules •

See other products used in the treatment of •pneumonia •respiratory tract infections •

Dosage depends largely on the type and severity of the infection being treated. In the treatment of respiratory tract infections, doses for adults range from 150 to 450 mg every 6 hours.

Clindamycin is an antibiotic medication that kills various bacteria. It works by inhibiting protein synthesis, resulting in bacterial cell death. The effectiveness of clindamycin depends on factors such as dose, concentration in the blood and other body fluids and tissues, and the susceptibility of the bacteria. Clindamycin does not kill all types of bacteria, but only those that have a sensitivity to this antibiotic. Infections caused by bacteria that are not sensitive to clindamycin will not show improvement after taking this medication.

Along with its needed effects, clindamycin may cause some unwanted or undesirable effects. Generally, clindamycin is well tolerated and many people will not experience unwanted effects. The frequency and severity of these effects is dependant on many factors including dose, duration of therapy and individual susceptibility. Possible unwanted effects include:

  • diarrhea
  • nausea
  • rash


  • vomiting
  • mouth sores
  • sore throat
  • bloody stools
  • pseudomembranous colitis (inflammation of the colon caused by the overgrowth and toxin production of bacteria that are not killed by the antibiotic)


Allergic reactions can occur with clindamycin use. The reaction can be immediate and severe. Allergic symptoms include wheezing, hives, itching, swelling, joint and muscle pain, difficulty breathing, fever and skin rashes. Nausea and vomiting are not symptoms of an allergic reaction.

Taking the antibiotic repeatedly or for prolonged periods may result in bacterial or fungal overgrowth which can lead to a second infection. When this occurs, the clindamycin may need to be stopped and another antibiotic prescribed to treat the new infection.
Diarrhea often develops while taking clindamycin. This is sometimes caused by an overgrowth of bacteria in the gut that are not killed by the antibiotic. In severe cases, this may be life threatening and would require treatment with other antibiotics. In mild cases, symptoms disappear shortly after the drug is discontinued.
Drug Interactions: It is important to tell your doctor and pharmacist of any prescription or over-the-counter medications you are taking. 

  • BCG vaccine
  • erythromycin
  • mycophenolate
  • primaquine
  • sodium picosulfate
  • typhoid vaccine

Use is not recommended in the following situations:

  • allergy to clindamycin or lincomycin
  • infants younger than 30 days

Caution is recommended in the following situations:

  • diarrhea
  • colitis or other digestive tract diseases
  • liver disease

Use in pregnancy: Considered compatible with pregnancy.  Consult your doctor or pharmacist if you suspect you are pregnant.
Use while breastfeeding: Clindamycin does appear in breast-milk. Consult your doctor or pharmacist before use.